PhD (all genders) in molecular oncology

The UKE offers the opportunity to perform cutting-edge research within an excellent research environment. The junior research group of Priv.-Doz. Dr. Johann von Felden (homepage: www.vonfeldenlab.com) focusses on translational research projects in the field of oncology, with the main objective to derive molecular biomarkers for implementing personalized cancer care for patients with liver cancer. We aim at deciphering mechanisms of hepatocarcinogenesis and identifying biomarkers to predict the response to therapies or improve early cancer detection. We utilize state-of-the-art technologies and modern analytical pipelines, incl. gene editing, murine liver cancer models, next-generation sequencing, and liquid biopsy approaches.

Your tasks:

• To continue our established biobank
• To plan and execute experiments, including the establishment of novel protocols and techniques incl.
  • Genetically engineered murine liver cancer models (major focus of the project)
  • gene transfer with lentiviral vectors in cell culture and organoid models
  • gene expression analysis (e.g. PCR)
  • functional analysis incl. proliferation and migration assays
  • cell sorting and FACS
• General and administrative tasks in the laboratory

This position is, in accordance with the WissZeitVG, temporary for 3 years (65% of regular working hours).

• Academic degree in molecular life sciences, biology, biocehmistry, immunology or related field
• Previous research experience, particularly in the above-mentioned techniques, would be preferred
• Previous experience in the field of oncology is preferred
• Good knowledge in English, both written and spoken
• Very good experience in MS Office; previous experience with data analysis, e.g. R is preferred
• Thorough and structured attitude, solution oriented
• Ability to work in a team
• Eager to learn, and readiness of mind

Immunity status
Please note that employment is contingent upon proof of immunization or immunity against the measles virus, in accordance with applicable legal and medical requirements. Documentation (e.g., vaccination certificate) must be provided before employment begins.

• Attractive compensation according to TVöD/VKA
• Secure employment with meaningful work and respectful collaboration
• Comprehensive onboarding and open knowledge exchange within the team
• Extensive training and further education programs at our UKE Academy for Education and Careers
• Opportunities to contribute to our “UKE INside” personnel policy through cross-professional and cross-hierarchical projects
• Sustainable travel: subsidies for the Deutschlandticket as a job ticket, and Dr. Bike bicycle service
• Family-friendly working environment: cooperation on childcare, free vacation childcare, advice for employees with relatives in need of care
• Excellent health, wellness, and sports programs
• A wide range of dining options in our staff restaurant, with additional choices available at the “Health Kitchen” cafés, bistros, and an on-site supermarket

About us

We live diversity and value variety
We offer a work environment that provides equal opportunities regardless of age, gender, sexual identity, disability, ethnic and social origin, or religion. This is confirmed by our accession to the Charter of Diversity. We explicitly aim to increase the proportion of women in management positions, especially among scientific personnel in research and teaching. Women with equal qualifications will be given priority. The same applies in the case of under-representation of one gender in the advertised area. Persons with severe disabilities with equal aptitude, competence, and professional performance will be given priority.