Header image Universitätsklinikum Münster

PhD Student (gn*) Biology, Biochemistry, Biomedicine, Experimental Medicine, Medicine

Fixed-term of three years | Part-time with 65% (25 hours/week) | Salary according to TV-L E13 | Department of Anesthesiology, Intensive Care and Pain Therapy | Job ID: 10580

We are UKM. We have a clear social mission and, with our focus on healthcare, research, and teaching, we bear a unique responsibility.

To meet our high standards every day, we are looking forward to your scientific expertise in the Department of Anesthesiology, Intensive Care and Pain Therapy - ideally with you on board!

The Jorch Lab studies the mechanisms of immune cell activation and recruitment in various in vitro and in vivo models of inflammation and infections. In detail, this project addresses the functional analysis of PSTPIP1, a protein that is relevant in certain autoinflammatory diseases, and the alarmins S100A8/A9 in inflammasome activation using mainly biochemical and cell biological methods.

This project provides an exciting and dynamic research environment with a broad range of state-of-the-art technologies from various departments, with excellent opportunities for networking and collaboration.

Your Tasks

Culture of immortalized cell lines
Generation of mutant cell lines via CRISPR/Cas9
In vitro interaction studies with recombinant proteins and in vivo interaction studies using immortalized cell lines
Functional assays including inflammasome activation, cytokine release, ROS production, phagocytosis, adhesion and migration

What we expect:

Master's degree in biology, biochemistry, biomedicine, experimental medicine, medicine or other related subjects/life sciences
Strong knowledge in molecular biology, biochemical and immunological techniques such as western blot, flow cytometry, cell culture, ELISA
Experience in working with mice or imaging techniques is not essential, but would be beneficial
An independent, reliable and structured way of working with a focus on quality is essential
Motivation , flexibility, good self-organization, and team working abilities
Willingness to analyze and critically reflect scientific data
Determination, profound knowledge and resilience to successfully complete the project and advance the scientific field
Good written and spoken English language skills
Strong interest in doing and understanding science
Willingness to organize and prioritize work

What we offer:

Training, further development and working with state-of-the-art technologies in inflammation research
Participation in and contribution to scientific group meetings, network meetings and conferences
Encouragement and support for the preparation of research papers and scientific networking
Excellent options for networking and collaboration through collaborative research networks
An exciting and dynamic research environment
Support for personal development and training

BENEFITS

Exciting Projects
Professional Development and Training
Interdisciplinary Collaboration
Part of Research Innovation
Additional Benefits

Apply now via the application-button until 07.05.2025 including:

A cover letter with a brief statement of research experience, research interests, research techniques, and career goals
A CV with education certificates and grades
Contact information of two possible referees (address, phone number and email)

(*gn=gender neutral)

The University Hospital of Münster is one of the leading hospitals in Germany. Such a position cannot be achieved by size and medical successes alone. The individual commitment counts above all. We need your commitment so that even with little things we can achieve great things for our patients. There are many possibilities open for you so that you may develop with them.

Universitätsklinikum Münster
Albert-Schweitzer-Campus 1, Gebäude D5
48149 Münster
www.ukm.de

Apply now

Full-Time , Temporary

PhD Project

Updated at 04/10/2025

While applying for the job please refer to jobvector and use the following reference number: 10580