COMPUTATIONAL GENOMICS SCIENTIST (m/f/d)
Full time - Mainz
We are looking for a new team member in our Computational Medicine unit to start as soon as possible. The Computational Medicine unit is an interdisciplinary team of scientists, software developers, and PhD students, with diverse backgrounds, including computer science, molecular biotechnology, bioinformatics, and mathematics. We strongly collaborate with other units in TRON and with external partners to develop software, predictive models, and data analysis to identify biomarkers and targets for innovative immunotherapies against cancer and other diseases. The successful candidate will support the analysis of sequencing data with established workflows or by implementing novel pipelines to address diverse research questions.
Your tasks and responsibilities:
- Providing reproducible analyses with bioinformatics workflows of sequencing data (Illumina, ONT, PacBio) for diverse translational research projects
- Maintainance and further develop our internal and open source bioinformatics workflows
- Testing, comparing and systematically benchmarking novel bioinformatic tools and predicitve models using (internal) experimental confirmation data for highly accurate results in translational research questions
- Designe and supervise the implementation of novel pipelines and analysis workflows
- Support the planing of sequencing and wet-lab validation experiments for genomics projects in collaboration with other units and external partners
- Presenting and discussing your work in meetings and at conferences, write reports and publish manuscripts
What you bring:
- A PhD in bioinformatics, computational biology or equivalent and a track record in computational genomics
- Proven proficiency in analyzing NGS data (e.g. WGS, WES, RNA-seq, ATAC-seq, short/long-read sequencing data)
- Proficiency working in a Linux HPC environment, including the use of job schedulers, virtual environments, and containerization
- Strong programming experience, preferably in Python and R
- Hands-on experience with collaborative software development tools (e.g. git, GitLab, GitHub), dependency management (conda, docker, singularity), and computational workflow managers (e.g. NextFlow, snakemake)
- An excellent data visualization and communication skills
Enthusiasm and curiosity for the diverse activities of our research institute as well as the ability to work in a team completes your profile.
We offer:
- A dynamic, innovative and creative research environment
- An open, collegial and cordial working atmosphere in a respectful corporate culture
- A high degree of diversity in the workforce
- Flat hierarchies
- Performance-related remuneration and other benefits
- The opportunity for personalised further training
- Good transport connections by public transport and car as well as bicycle parking spaces
- The opportunity for hybrid working