Max-Planck-Institut für Multidisziplinäre Naturwissenschaften

Single molecule X-ray scattering experiments with free electron lasers offer a new route to the structure determination of biomolecules. Due to the super-low signal-to-noise ratio, computing the structure from such data is challenging, and new theoretical methods and algorithms a...

Possible projects are variational free energy methods, thermodynamics of solvation shells, constant-pH simulation methods, Markovian thermodynamics, as well as functional mechanisms of the ribosome, fatty acid synthase, CRISPR/Cas, or intrinsically disordered proteins. Pleas...