The Structural Bioenergetics Group is interested in energy converting enzyme complexes of the respiratory chain. Our main focus is the structure and function of mitochondrial complex I (NADH:ubiquinone oxidoreductase).
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The PhD project aims to isolate assembly intermediates of respiratory complex I and to determine their molecular structure. We are working with a yeast that can be easily genetically modified, e.g. for generating tagged variants of assembly factors. We plan to establish the nemat...